Nodules, sebum, bacteria and scarring

Cystic acne

Acne turns cystic when lumps fill with pus deep under the skin of the face, back, chest or shoulders and can last for months. Lumps found only where skin touches skin, like the armpits or groin, point to hidradenitis suppurativa.

Where do your deep lumps sit?

Hard to judge in a mirror? A face scan of about half a minute comes first, then a few short questions.

Last reviewed


Cystic acne or something else?

Three other deep lumps get mistaken for cystic acne. Two answers show which one yours looks like.

Cystic acne sits where oil glands are busiest; lumps only in skin folds point elsewhere
  • Acne zones
  • Skin folds
Where is it?
What does it look like?
Do you feel unwell or feverish?

Pick an answer for where it is and what it looks like.

Deep lumps compared
LumpWhereWhat it looks likeWho treats it
Cystic acneFace, jaw, neck, chest, back, shouldersDeep, painful lumps full of pusA dermatologist
Hidradenitis suppurativaArmpits, inner thighs, groin, buttocks, under the breastsLumps that return in the same spot and leak blood and pus; not contagiousA dermatologist
BoilFace, neck, armpits, buttocks, thighsOne tender, swollen spot that fills with pus, usually from staph bacteriaA doctor or urgent care
Epidermoid cystChest, shoulders, faceA firm, round lump with a tiny pore and cheesy contents; twice as common in menA dermatologist, by minor surgery

Hidradenitis suppurativa affects about 1 in 100 people (NHS). Warm compresses help a boil drain (MedlinePlus).


What cystic acne is

Cystic acne is the most severe form of acne, with deep, painful lumps full of pus. It means the trouble starts deep in the skin, not at the surface. The cause of cystic acne is a hair follicle plugged with oil and dead skin cells: skin bacteria grow in the plug, and when the follicle wall breaks down, the contents spill into the skin and inflame it (NIAMS).

Doctors also call it severe nodular acne or nodulocystic acne (NIAMS, MedlinePlus). Acne "cysts" have no capsule of their own, so dermatologists call them pseudocysts (DermNet).


Symptoms and Characteristics

Appearance
Nodules and cysts are larger lumps under the skin, and they may join together (NHS).
Pain
Deep breakouts tend to hurt (AAD, NHS).
Common Locations
Face, jawline, neck, chest, back, sometimes the buttocks (AAD), and shoulders (NIAMS). Lumps on the trunk tend to linger and scar differently; see cystic acne on the back and chest.
Duration
A regular spot clears in under two weeks; a deep lump can last months (DermNet), and scars often follow (AAD).

If those four sound familiar, a photo can rate how severe your breakouts are.


Causes and Triggers

Pore Blockage

Oil and dead skin cells clog a hair follicle, bacteria grow inside, and the wall gives way deep down (NIAMS).

Hormones

Androgens rise in puberty and enlarge oil glands (AAD); periods, pregnancy and the pill shift oil too (MedlinePlus). Acne with irregular periods or extra facial hair can point to PCOS, which the NHS now calls PMOS (AAD).

Genetics & Lifestyle

A close relative with deep, painful pimples raises your risk, and stress may worsen acne (AAD). Anabolic steroids and whey supplements are risk factors (DermNet). A sugar or dairy link is unproven; MedlinePlus calls it controversial.


Treatments

What dermatologists use for cystic acne
OptionWhat it isWhat it does for deep lumpsWho gives it
Prescription TopicalsA retinoid, benzoyl peroxide or azelaic acidKeeps pores clear; alone, usually not enough for deep lumps (DermNet)Ask your dermatologist
Oral MedicationsAn antibiotic with a medicine you apply; for women, the pill or spironolactoneOften the first plan (AAD); spironolactone is not prescribed for menAsk your dermatologist
IsotretinoinOne course of pills, with a required monitoring programAbout 85% see permanent clearing after one course (AAD); a 2024 US guideline strongly recommends it for severe or scarring acneAsk your dermatologist
In-Office ProceduresA corticosteroid shot, or incision and drainageThe shot quickly shrinks one big, painful lump; drainage is for one medicine cannot clear (AAD)A dermatologist
At-Home CareIce, and hands offIce eases pain; never drain a lump yourself, the infection risk is high (AAD)You

Store products cannot clear severe acne, and waiting it out can take years (AAD).


Going deeper on cystic acne

If you want to know what is going on under the skin, and why these lumps are not true cysts, start with what is cystic acne.

Lumps that swell along the jaw before each period follow a pattern of their own, explained under hormonal cystic acne.

Every prescription route, from tablets to injections, is weighed side by side under cystic acne treatment.


When to see a doctor

  • Any deep, painful lump: the sooner a dermatologist treats it, the fewer scars (AAD).
  • Hot, swollen, red skin around the spots, a sign of infection (NHS).
  • A boil on your face, or a boil while you feel hot or shivery (NHS).
  • Acne plus signs of PCOS (AAD).
  • Acne that weighs on your mood (NHS).

Quick answers

What is cystic acne caused by?

A plugged hair follicle that bursts deep in the skin (NIAMS). Puberty hormones and a family history of deep pimples make it more likely (AAD).

What is mistaken for cystic acne?

Hidradenitis suppurativa (lumps in skin folds), a boil (one infected follicle) and an epidermoid cyst (a round lump with a tiny pore). The sorter above tells them apart.

Does cystic acne mean PCOS?

Not by itself. PCOS affects 7 to 10% of women of childbearing age, and 60 to 80% of them have high androgen levels (Endocrine Society). Other signs are irregular periods, extra facial hair, thinning scalp hair or darkening skin (AAD).

How to tell if a pimple is cystic acne?

It is a large, painful lump under the skin, not a small bump on top, and it lasts far longer than the two weeks of a regular spot (NHS, DermNet).

What draws out a cystic pimple?

Nothing safe at home: squeezing pushes it deeper. Ice eases pain; a dermatologist can inject or drain it (AAD).


Sources

  1. What can clear severe acne? American Academy of Dermatology (AAD).
  2. Types of acne; Pimple popping; What causes acne; Hormonal therapy; Stubborn acne; Diet and acne. AAD.
  3. Hidradenitis suppurativa: overview; signs and symptoms. AAD.
  4. Hidradenitis suppurativa; Boils; Acne. NHS.
  5. Boils; Acne. MedlinePlus, National Library of Medicine.
  6. Acne. NIAMS, National Institutes of Health.
  7. Epidermoid cyst; Cutaneous cysts and pseudocysts; Nodulocystic acne; Acne vulgaris. DermNet.
  8. Polycystic ovary syndrome. Endocrine Society.
  9. Guidelines of care for the management of acne vulgaris. JAAD, 2024. PMID 38300170.

General information, not a diagnosis. See a dermatologist for deep, painful lumps.